Construction of Metabolically Biotinylated Adenovirus with Deleted Fiber Knob as Targeting Vector
<p>Abstract</p> <p>Gene delivery vectors based on adenovirus, particularly human adenovirus serotype 5 (hAd5) have great potential for the treatment of variety of diseases. However, the tropism of hAd5 needs to be modified to achieve tissue- or cell- specific therapies for the succ...
Main Authors: | Schnitzer Jan E, Valadon Philippe, Liu Yanzheng |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-11-01
|
Series: | Virology Journal |
Online Access: | http://www.virologyj.com/content/7/1/316 |
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