Construction of Metabolically Biotinylated Adenovirus with Deleted Fiber Knob as Targeting Vector

<p>Abstract</p> <p>Gene delivery vectors based on adenovirus, particularly human adenovirus serotype 5 (hAd5) have great potential for the treatment of variety of diseases. However, the tropism of hAd5 needs to be modified to achieve tissue- or cell- specific therapies for the succ...

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Bibliographic Details
Main Authors: Schnitzer Jan E, Valadon Philippe, Liu Yanzheng
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/7/1/316