Characterization, Molecular Docking, and In Vitro Dissolution Studies of Solid Dispersions of 20(S)-Protopanaxadiol

Characterization, Molecular Docking, and In Vitro Dissolution Studies of Solid Dispersions of 20(S)-Protopanaxadiol

In this study, we prepared solid dispersions (SDs) of 20(S)-protopanaxadiol (PPD) using a melting-solvent method with different polymers, in order to improve the solubility and dissolution performance of drugs with poor water solubility. The SDs were characterized via differential scanning calorimet...

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Bibliographic Details
Main Authors: Qi Zhang, Yiqiong Pu, Bing Wang, Yuqin Wang, Tina Tingxia Dong, Tao Guo, Tong Zhang, Zhenzhen Cai
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Molecules
Subjects:
20(S)-protopanaxadiol
solid dispersion
polymer
molecular docking
in vitro dissolution
Online Access:http://www.mdpi.com/1420-3049/22/2/274

Internet

http://www.mdpi.com/1420-3049/22/2/274

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