The effect of thyroxin on hepatic redox equilibrium and lipid metabolism in rats treated with doxorubicin

The effect of thyroxin on hepatic redox equilibrium and lipid metabolism in rats treated with doxorubicin

The main side effects of the administration of doxorubicin, a widely used anticancer drug, is the generation of a reactive oxygen species (ROS) in normal cells. As a result, redox disorders and secondary oxidative stress are developed. Doxorubicin ROS generation is attributed to enzymes that are pro...

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Bibliographic Details
Main Authors: Czuba Bartosz, Fituch Magdalena, Mandziuk Slawomir, Jodlowska-Jedrych Barbara, Matysiak Wlodzimierz, Halasa Justyna, Burdan Franciszek, Korga Agnieszka, Iwan Magdalena, Luszczewska-Sierakowska Iwona, Dudka Jarosław
Format: Article
Language:English
Published: Sciendo 2014-12-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
doxorubicin
thyroxin
liver
redox equilibrium
lipid metabolism
Online Access:https://doi.org/10.1515/cipms-2015-0019

Internet

https://doi.org/10.1515/cipms-2015-0019

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