Opposing Cholinergic and Serotonergic Modulation of Layer 6 in Prefrontal Cortex

Prefrontal cortex is a hub for attention processing and receives abundant innervation from cholinergic and serotonergic afferents. A growing body of evidence suggests that acetylcholine (ACh) and serotonin (5-HT) have opposing influences on tasks requiring attention, but the underlying neurophysiolo...

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Bibliographic Details
Main Authors: Daniel W. Sparks, Michael K. Tian, Derya Sargin, Sridevi Venkatesan, Katheron Intson, Evelyn K. Lambe
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fncir.2017.00107/full