The Protective Effect of Vanadium on Cognitive Impairment and the Neuropathology of Alzheimer’s Disease in APPSwe/PS1dE9 Mice

The Protective Effect of Vanadium on Cognitive Impairment and the Neuropathology of Alzheimer’s Disease in APPSwe/PS1dE9 Mice

Alzheimer’s disease (AD) is a widely distributed neurodegenerative disease characterized clinically by cognitive deficits and pathologically by formation of amyloid-β (Aβ) plaque and neurofibrillary tangles (NFTs) in the brain. Vanadium is a biological trace element that has a function to mimic insu...

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Bibliographic Details
Main Authors: Zhijun He, Shuangxue Han, Huazhang Zhu, Xia Hu, Xiaoqian Li, Chaofan Hou, Chong Wu, Qingguo Xie, Nan Li, Xiubo Du, Jiazuan Ni, Qiong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Alzheimer’s disease
amyloid beta (Aβ)
vanadium
bis(ethylmaltolato) oxidovanadium (IV) (BEOV)
peroxisome proliferator-activated receptor gamma (PPARγ)
protein tyrosine phosphatase-1B (PTP1B)
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00021/full

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https://www.frontiersin.org/article/10.3389/fnmol.2020.00021/full

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