Let-7a regulates EV secretion and mitochondrial oxidative phosphorylation by targeting SNAP23 in colorectal cancer

Let-7a regulates EV secretion and mitochondrial oxidative phosphorylation by targeting SNAP23 in colorectal cancer

Abstract Background MicroRNAs (miRNAs) are abundant in tumor-derived extracellular vesicles (EVs) and the functions of extracellular miRNA to recipient cells have been extensively studied with tumorigenesis. However, the role of miRNA in EV secretion from cancer cells remains unknown. Methods qPCR a...

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Bibliographic Details
Main Authors: You Dong Liu, Xiao Peng Zhuang, Dong Lan Cai, Can Cao, Qi Sheng Gu, Xue Ni Liu, Bin Bin Zheng, Bing Jie Guan, Liang Yu, Ji Kun Li, Hui Bin Ding, Dong Wang Yan
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Let-7a
SNAP23
Colorectal Cancer
Extracellular vesicles
Oxidative phosphorylation
Online Access:https://doi.org/10.1186/s13046-020-01813-6

Internet

https://doi.org/10.1186/s13046-020-01813-6

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