A Critical Balance: dNTPs and the Maintenance of Genome Stability

A Critical Balance: dNTPs and the Maintenance of Genome Stability

A crucial factor in maintaining genome stability is establishing deoxynucleoside triphosphate (dNTP) levels within a range that is optimal for chromosomal replication. Since DNA replication is relevant to a wide range of other chromosomal activities, these may all be directly or indirectly affected...

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Bibliographic Details
Main Authors: Chen‐Chun Pai, Stephen E. Kearsey
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Genes
Subjects:
dNTP
DNA polymerase
genome instability
ribonucleotide reductase
replication fidelity
proofreading
Online Access:http://www.mdpi.com/2073-4425/8/2/57

Internet

http://www.mdpi.com/2073-4425/8/2/57

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