Artesunate-induced mitophagy alters cellular redox status

Artesunate-induced mitophagy alters cellular redox status

Artesunate (ART) is a prominent anti-malarial with significant anti-cancer properties. Our previous studies showed that ART enhances lysosomal function and ferritin degradation, which was necessary for its anti-cancer properties. ART targeting to mitochondria also significantly improved its efficacy...

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Bibliographic Details
Main Authors: Jianbin Zhang, Xin Sun, Liming Wang, Yin Kwan Wong, Yew Mun Lee, Chao Zhou, Guoqing Wu, Tongwei Zhao, Liu Yang, Liqin Lu, Jianing Zhong, Dongsheng Huang, Jigang Wang
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718301757

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http://www.sciencedirect.com/science/article/pii/S2213231718301757

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