Targeting Phosphodiesterases—Towards a Tailor-Made Approach in Multiple Sclerosis Treatment

Targeting Phosphodiesterases—Towards a Tailor-Made Approach in Multiple Sclerosis Treatment

Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system (CNS) characterized by heterogeneous clinical symptoms including gradual muscle weakness, fatigue, and cognitive impairment. The disease course of MS can be classified into a relapsing-remitting (RR) phase defin...

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Bibliographic Details
Main Authors: Melissa Schepers, Assia Tiane, Dean Paes, Selien Sanchez, Ben Rombaut, Elisabeth Piccart, Bart P. F. Rutten, Bert Brône, Niels Hellings, Jos Prickaerts, Tim Vanmierlo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
phosphodiesterase
neuroinflammation
CNS repair
remyelination
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01727/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01727/full

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