Rab GTPase prenylation hierarchy and its potential role in choroideremia disease.

Rab GTPase prenylation hierarchy and its potential role in choroideremia disease.

Protein prenylation is a widespread post-translational modification in eukaryotes that plays a crucial role in membrane targeting and signal transduction. RabGTPases is the largest group of post-translationally C-terminally geranylgeranylated. All Rabs are processed by Rab geranylgeranyl-transferase...

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Bibliographic Details
Main Authors: Monika Köhnke, Christine Delon, Marcus L Hastie, Uyen T T Nguyen, Yao-Wen Wu, Herbert Waldmann, Roger S Goody, Jeffrey J Gorman, Kirill Alexandrov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3864799?pdf=render

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http://europepmc.org/articles/PMC3864799?pdf=render

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