Review: Synthetic scaffolds to control the biochemical, mechanical, and geometrical environment of stem cell-derived brain organoids

Stem cell-derived brain organoids provide a powerful platform for systematic studies of tissue functional architecture and the development of personalized therapies. Here, we review key advances at the interface of soft matter and stem cell biology on synthetic alternatives to extracellular matrices...

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Bibliographic Details
Main Authors: Mariana Oksdath, Sally L. Perrin, Cedric Bardy, Emily F. Hilder, Cole A. DeForest, R. Dario Arrua, Guillermo A. Gomez
Format: Article
Language:English
Published: AIP Publishing LLC 2018-12-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/1.5045124