Loss of BRCA1 Spontaneously Induces the Tumorigenesis in Lacrimal Gland

Environmental and genetic factors exert important influences on lifespan and neoplastic transformation. We have previously shown that spontaneous tumors form frequently in mice homozygous for a full-length Brca1 deletion. In general, mutations of BRCA1 are closely associated with induction of breast...

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Bibliographic Details
Main Authors: Sun Eui Kim, Hye Jung Baek, Eun Jung Park, Sung Chul Lim, Sang Soo Kim
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2018/8120579