BRG1 Mediates Nephronectin Activation in Hepatocytes to Promote T Lymphocyte Infiltration in ConA-Induced Hepatitis

BRG1 Mediates Nephronectin Activation in Hepatocytes to Promote T Lymphocyte Infiltration in ConA-Induced Hepatitis

Fulminant hepatitis (FH) is a major cause of acute liver failure. Concanavalin A (ConA) belongs to the lectin family and is frequently used as an inducer of FH in animal models. ConA induced FH is characterized by massive accumulation of T lymphocytes in the liver. A host of chemoattractive substanc...

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Bibliographic Details
Main Authors: Wenxuan Hong, Ming Kong, Mengwen Qi, Hui Bai, Zhiwen Fan, Ziyu Zhang, Aijun Sun, Xiangshan Fan, Yong Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
transcriptional regulation
fulminant hepatitis
T lymphocyte
chemokine
nephronectin
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.587502/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.587502/full

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