Genome-Wide Target Analyses of Otx2 Homeoprotein in Postnatal Cortex

Genome-Wide Target Analyses of Otx2 Homeoprotein in Postnatal Cortex

Juvenile brain has a unique time window, or critical period, in which neuronal circuits are remodeled by experience. Mounting evidence indicates the importance of neuronal circuit rewiring in various neurodevelopmental disorders of human cognition. We previously showed that Otx2 homeoprotein, essent...

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Bibliographic Details
Main Authors: Akiko Sakai, Ryuichiro Nakato, Yiwei Ling, Xubin Hou, Norikazu Hara, Tomoya Iijima, Yuchio Yanagawa, Ryozo Kuwano, Shujiro Okuda, Katsuhiko Shirahige, Sayaka Sugiyama
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Neuroscience
Subjects:
Otx2
parvalbumin
ChIP-seq
critical period
neurodevelopmental disorder
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00307/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00307/full

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