Bacterial Sigma Factors and Anti-Sigma Factors: Structure, Function and Distribution
Sigma factors are multi-domain subunits of bacterial RNA polymerase (RNAP) that play critical roles in transcription initiation, including the recognition and opening of promoters as well as the initial steps in RNA synthesis. This review focuses on the structure and function of the major sigma-70 c...
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Format: | Article |
Language: | English |
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MDPI AG
2015-06-01
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Series: | Biomolecules |
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Online Access: | http://www.mdpi.com/2218-273X/5/3/1245 |