Bacterial Sigma Factors and Anti-Sigma Factors: Structure, Function and Distribution

Sigma factors are multi-domain subunits of bacterial RNA polymerase (RNAP) that play critical roles in transcription initiation, including the recognition and opening of promoters as well as the initial steps in RNA synthesis. This review focuses on the structure and function of the major sigma-70 c...

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Bibliographic Details
Main Author: Mark S. Paget
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Biomolecules
Subjects:
RIP
Online Access:http://www.mdpi.com/2218-273X/5/3/1245