Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks

<p>Abstract</p> <p>Background</p> <p>An increasing number of studies support the presence of stem-like cells in human malignancies. These cells are primarily responsible for tumor initiation and thus considered as a potential target to eradicate tumors. CD133 has been i...

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Bibliographic Details
Main Authors: Wang Lei, Sasai Ken, Kimura Taichi, Tabu Kouichi, Bizen Norihisa, Nishihara Hiroshi, Taga Tetsuya, Tanaka Shinya
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/39