Clinical applications of polygenic breast cancer risk: a critical review and perspectives of an emerging field

Abstract Polygenic factors are estimated to account for an additional 18% of the familial relative risk of breast cancer, with those at the highest level of polygenic risk distribution having a least a twofold increased risk of the disease. Polygenic testing promises to revolutionize health services...

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Bibliographic Details
Main Authors: Tatiane Yanes, Mary-Anne Young, Bettina Meiser, Paul A. James
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Breast Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13058-020-01260-3