Concurrent YAP/TAZ and SMAD signaling mediate vocal fold fibrosis

Abstract Vocal fold (VF) fibrosis is a major cause of intractable voice-related disability and reduced quality of life. Excision of fibrotic regions is suboptimal and associated with scar recurrence and/or further iatrogenic damage. Non-surgical interventions are limited, putatively related to limit...

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Bibliographic Details
Main Authors: Ryosuke Nakamura, Nao Hiwatashi, Renjie Bing, Carina P. Doyle, Ryan C. Branski
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92871-z