Combining Protein Ligation Systems to Expand the Functionality of Semi-Synthetic Outer Membrane Vesicle Nanoparticles

Combining Protein Ligation Systems to Expand the Functionality of Semi-Synthetic Outer Membrane Vesicle Nanoparticles

Bacterial outer membrane vesicles (OMVs) attract increasing interest as immunostimulatory nanoparticles for the development of vaccines and therapeutic agents. We previously engineered the autotransporter protein Hemoglobin protease (Hbp) into a surface display carrier that can be expressed to high...

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Bibliographic Details
Main Authors: H. Bart van den Berg van Saparoea, Diane Houben, Coen Kuijl, Joen Luirink, Wouter S. P. Jong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Microbiology
Subjects:
autodisplay
protein display
outer membrane vesicle
vaccine
protein ligation
Spy
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00890/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00890/full

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