A pH/ROS cascade-responsive and self-accelerating drug release nanosystem for the targeted treatment of multi-drug-resistant colon cancer

A pH/ROS cascade-responsive and self-accelerating drug release nanosystem for the targeted treatment of multi-drug-resistant colon cancer

The efficacy of chemotherapeutic agents for colon cancer treatment is limited by multidrug resistance (MDR) and insufficient intracellular release of the administered nanomedicine. To overcome these limitations, we constructed a pH/ROS cascade-responsive and self-accelerating drug release nanopartic...

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Bibliographic Details
Main Authors: Na Chang, Yufei Zhao, Ning Ge, Liting Qian
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Drug Delivery
Subjects:
ros amplification
self-accelerate drug release
multidrug resistance
Online Access:http://dx.doi.org/10.1080/10717544.2020.1797238

Internet

http://dx.doi.org/10.1080/10717544.2020.1797238

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