Automated segmentation of thick confocal microscopy 3D images for the measurement of white matter volumes in zebrafish brains

Tissue clearing methods have boosted the microscopic observations of thick samples such as whole-mount mouse or zebrafish. Even with the best tissue clearing methods, specimens are not completely transparent and light attenuation increases with depth, reducing signal output and signal-to-noise ratio...

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Bibliographic Details
Main Authors: Lempereur Sylvain, Jenett Arnim, Machado Elodie, Arganda-Carreras Ignacio, Simion Matthieu, Affaticati Pierre, Joly Jean-Stéphane, Talbot Hugues
Format: Article
Language:English
Published: De Gruyter 2020-07-01
Series:Mathematical Morphology
Subjects:
Online Access:https://doi.org/10.1515/mathm-2020-0100