Nuclear detection of Y-<it>box </it>protein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer

<p>Abstract</p> <p>Background</p> <p>Y-box binding protein-1 (YB-1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus YB-1 protein orchestrates transcription of proliferation-related genes, whereas in the...

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Bibliographic Details
Main Authors: Wild Peter J, Fuchs Thomas, Breuer Elisabeth, Djudjaj Sonja, Krings Renate, Wiesmann Frank, En-Nia Abdelaziz, Dahl Edgar, Hartmann Arndt, Dunn Sandra E, Mertens Peter R
Format: Article
Language:English
Published: BMC 2009-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/410