A cross-metathesis approach to novel pantothenamide derivatives

Pantothenamides are known for their in vitro antimicrobial activity. Our group has previously reported a new stereoselective route to access derivatives modified at the geminal dimethyl moiety. This route however fails in the addition of large substituents. Here we report a new synthetic route that...

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Bibliographic Details
Main Authors: Jinming Guan, Matthew Hachey, Lekha Puri, Vanessa Howieson, Kevin J. Saliba, Karine Auclair
Format: Article
Language:English
Published: Beilstein-Institut 2016-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.12.95