Megakaryocyte lineage development is controlled by modulation of protein acetylation.

Megakaryocyte lineage development is controlled by modulation of protein acetylation.

Treatment with lysine deacetylase inhibitors (KDACi) for haematological malignancies, is accompanied by haematological side effects including thrombocytopenia, suggesting that modulation of protein acetylation affects normal myeloid development, and specifically megakaryocyte development. In the cur...

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Bibliographic Details
Main Authors: Marije Bartels, Anita Govers, Roel Polak, Stephin Vervoort, Ruben van Boxtel, Cornelieke Pals, Marc Bierings, Wouter van Solinge, Toine Egberts, Edward Nieuwenhuis, Michal Mokry, Paul James Coffer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5919413?pdf=render

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http://europepmc.org/articles/PMC5919413?pdf=render

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