LncRNA DGCR5 Isoform-1 Silencing Suppresses the Malignant Phenotype of Clear Cell Renal Cell Carcinoma via miR-211-5p/Snail Signal Axis

LncRNA DGCR5 Isoform-1 Silencing Suppresses the Malignant Phenotype of Clear Cell Renal Cell Carcinoma via miR-211-5p/Snail Signal Axis

Long non-coding RNAs (lncRNAs) play important roles during the initiation and progression of cancer. We identified DiGeorge Syndrome Critical Region Gene 5 (DGCR5) as a clear cell renal cell carcinoma (ccRCC) cancer- and lineage-specific lncRNA. Agarose gel electrophoresis analysis and sanger sequen...

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Bibliographic Details
Main Authors: Guang-Xin Zhong, Dan Luo, Yi-jun Fan, Jue Wang, Bing-Qiang Liu, Zhong-Hua Xu, Xiang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
DGCR5
cell proliferation
ceRNA
clear cell renal cell carcinoma
miR-211-5p
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.700029/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.700029/full

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