A Well-Controlled Experimental System To Study Interactions Of Cytotoxic T Lymphocytes With Tumor Cells

A Well-Controlled Experimental System To Study Interactions Of Cytotoxic T Lymphocytes With Tumor Cells

While T cell-based immunotherapies are steadily improving, there are still many patients who progress, despite T cell-infiltrated tumors. Emerging evidence suggests that T cells themselves may provoke immune escape of cancer cells. Here we describe a well-controlled co-culture system for studying th...

Full description

Bibliographic Details
Main Authors: Natalie Jessica Neubert, Charlotte Soneson, David Barras, Petra Baumgaertner, Donata Rimoldi, Mauro Delorenzi, Silvia A Fuertes Marraco, Daniel Ernst Speiser
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Immunology
Subjects:
Melanoma
CD8+ T cell
Antigen-specific
co-culture
NanoString
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00326/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00326/full

Similar Items