A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement

The global impact of somatic structural variants (SSVs) on gene expression in childhood cancers is unclear. Here, the authors analyse cancer genome and RNA sequencing data of 854 pediatric brain tumours and report a landscape of genes deregulated by SSVs.

Bibliographic Details
Main Authors: Yiqun Zhang, Fengju Chen, Lawrence A. Donehower, Michael E. Scheurer, Chad J. Creighton
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21081-y