Ultrasound-mediated disruption of the blood tumor barrier for improved therapeutic delivery

Ultrasound-mediated disruption of the blood tumor barrier for improved therapeutic delivery

The blood-brain barrier (BBB) is a major anatomical and physiological barrier limiting the passage of drugs into brain. Central nervous system tumors can impair the BBB by changing the tumor microenvironment leading to the formation of a leaky barrier, known as the blood-tumor barrier (BTB). Despite...

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Bibliographic Details
Main Authors: T.A. Arsiwala, S.A. Sprowls, K.E. Blethen, C.E. Adkins, P.A. Saralkar, R.A. Fladeland, W. Pentz, A. Gabriele, B. Kielkowski, R.I. Mehta, P. Wang, J.S. Carpenter, M. Ranjan, U. Najib, A.R. Rezai, P.R. Lockman
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Focused ultrasound
Blood-brain barrier
Blood-tumor barrier
Permeability
Drug delivery
Disruption
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558621000257

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http://www.sciencedirect.com/science/article/pii/S1476558621000257

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