Calcium Channels in Postnatal Development of Rat Pancreatic Beta Cells and Their Role in Insulin Secretion

Calcium Channels in Postnatal Development of Rat Pancreatic Beta Cells and Their Role in Insulin Secretion

Pancreatic beta cells during the first month of development acquire functional maturity, allowing them to respond to variations in extracellular glucose concentration by secreting insulin. Changes in ionic channel activity are important for this maturation. Within the voltage-gated calcium channels...

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Bibliographic Details
Main Authors: Neivys García-Delgado, Myrian Velasco, Carmen Sánchez-Soto, Carlos Manlio Díaz-García, Marcia Hiriart
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Endocrinology
Subjects:
low-voltage-activated and high-voltage-activated calcium channels
postnatal development
insulin secretion
reverse hemolytic plaque assay
beta-cell maturation
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00040/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2018.00040/full

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