Parthenolide Induces Apoptosis in Committed Progenitor AML Cell line U937 via Reduction in Osteopontin

Background: Interfering with cell proliferation and survival is a critical role for antineoplastic drugs leading to cell death through induction of apoptosis. Alternative treatments with herbal extracts offer insights into acute myeloid leukemia (AML) therapy. Parthenolide (PTL), an extract from fev...

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Bibliographic Details
Main Authors: Mahdi Zahedpanah, Mojgan Shaiegan, Seyed Hamidollah Ghaffari, Mohsen Nikbakht, Mahin Nikugoftar, Saeed Mohammadi
Format: Article
Language:English
Published: Varastegan Institute for Medical Sciences 2016-05-01
Series:Reports of Biochemistry and Molecular Biology
Subjects:
Online Access:http://rbmb.net/article-1-75-en.pdf