Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex

Fast spiking interneurons provide perisomatic inhibition in the cortex. Here, Baohan et al. show the failure to develop perisomatic inhibition in heterozygous PTENnull mutant mouse and the underlying mechanism to EphB4 reduction in an experience-dependent manner.

Bibliographic Details
Main Authors: Amy Baohan, Taruna Ikrar, Elaine Tring, Xiangmin Xu, Joshua T. Trachtenberg
Format: Article
Language:English
Published: Nature Publishing Group 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12829