Human IgM monoclonal antibodies block HIV-transmission to immune cells in cervico-vaginal tissues and across polarized epithelial cells in vitro
Abstract The importance of natural IgM antibodies in protection against infections is still emerging and these antibodies have a potential role in the maintenance of homeostasis through clearance of apoptotic bodies, complement-dependent mechanisms, inflammation and exclusion of misfolded proteins....
Main Authors: | Claudia Devito, Rada Ellegård, Tina Falkeborn, Lennart Svensson, Mats Ohlin, Marie Larsson, Kristina Broliden, Jorma Hinkula |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-28242-y |
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