Human IgM monoclonal antibodies block HIV-transmission to immune cells in cervico-vaginal tissues and across polarized epithelial cells in vitro

Abstract The importance of natural IgM antibodies in protection against infections is still emerging and these antibodies have a potential role in the maintenance of homeostasis through clearance of apoptotic bodies, complement-dependent mechanisms, inflammation and exclusion of misfolded proteins....

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Bibliographic Details
Main Authors: Claudia Devito, Rada Ellegård, Tina Falkeborn, Lennart Svensson, Mats Ohlin, Marie Larsson, Kristina Broliden, Jorma Hinkula
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-28242-y