Mesenchymal stem cell-derived extracellular vesicles may promote breast cancer cell dormancy

Disseminated breast cancer cells have the capacity to metastasise to the bone marrow and reside in a dormant state within the mesenchymal stem cell niche. Research has focussed on paracrine signalling factors, such as soluble proteins, within the microenvironment. However, it is now clear extracellu...

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Bibliographic Details
Main Authors: Jake Casson, Owen G Davies, Carol-Anne Smith, Matthew J Dalby, Catherine C Berry
Format: Article
Language:English
Published: SAGE Publishing 2018-12-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731418810093