Four-dimensional NOE-NOE spectroscopy of SARS-CoV-2 Main Protease to facilitate resonance assignment and structural analysis

<p>Resonance assignment and structural studies of larger proteins by nuclear magnetic resonance (NMR) can be challenging when exchange broadening, multiple stable conformations, and <span class="inline-formula"><sup>1</sup></span>H back-exchange of the fully d...

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Bibliographic Details
Main Authors: A. J. Robertson, J. Ying, A. Bax
Format: Article
Language:English
Published: Copernicus Publications 2021-04-01
Series:Magnetic Resonance
Online Access:https://mr.copernicus.org/articles/2/129/2021/mr-2-129-2021.pdf