Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis

The metacestode stage of the fox tapeworm Echinococcus multilocularis causes the lethal disease alveolar echinococcosis. Current chemotherapeutic treatment options are based on benzimidazoles (albendazole and mebendazole), which are insufficient and hence alternative drugs are needed. In this study,...

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Bibliographic Details
Main Authors: Reto Rufener, Luca Dick, Laura D'Ascoli, Dominic Ritler, Amani Hizem, Timothy N.C. Wells, Andrew Hemphill, Britta Lundström-Stadelmann
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320718301222