Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complex.

Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complex.

Human Cytomegalovirus (HCMV) utilizes two different pathways for host cell entry. HCMV entry into fibroblasts requires glycoproteins gB and gH/gL, whereas HCMV entry into epithelial and endothelial cells (EC) requires an additional complex composed of gH, gL, UL128, UL130, and UL131A, referred to as...

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Bibliographic Details
Main Authors: Felix Wussow, Flavia Chiuppesi, Joy Martinez, John Campo, Erica Johnson, Christin Flechsig, Maegan Newell, Elaine Tran, Jose Ortiz, Corinna La Rosa, Andreas Herrmann, Jeff Longmate, Rana Chakraborty, Peter A Barry, Don J Diamond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4239111?pdf=render

Internet

http://europepmc.org/articles/PMC4239111?pdf=render

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