Opportunities and Limitations of Modelling Alzheimer’s Disease with Induced Pluripotent Stem Cells

Opportunities and Limitations of Modelling Alzheimer’s Disease with Induced Pluripotent Stem Cells

Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) has opened the way for patient-specific disease modelling. Following their differentiation into neuronal cell types, iPSC have enabled the investigation of human neurodegenerative diseases, such as Alzheimer’s disease (AD). W...

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Bibliographic Details
Main Authors: Dmitry A. Ovchinnikov, Ernst J. Wolvetang
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Journal of Clinical Medicine
Subjects:
induced pluripotent stem cells
Alzheimer’s disease
disease modelling
reprogramming
Online Access:http://www.mdpi.com/2077-0383/3/4/1357

Internet

http://www.mdpi.com/2077-0383/3/4/1357

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