Membrane dynamics, cholesterol homeostasis, and Alzheimer's disease
Alzheimer's disease (AD) is characterized by the deposition of β-amyloid (Aβ) plaques derived from the amyloidogenic processing; of a transmembrane protein called β-amyloid precursor protein (APP). In addition to the known genetic/sporadic factors that promote the formation of Aβ, the compositi...
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| Format: | Article |
| Language: | English |
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Elsevier
2003-11-01
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| Series: | Journal of Lipid Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520336750 |