Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice

<p>Abstract</p> <p>Neuronal nitric oxide synthase (nNOS) is a key enzyme for nitric oxide production in neuronal tissues and contributes to the spinal central sensitization in inflammatory pain. However, the role of nNOS in neuropathic pain remains unclear. The present study combin...

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Bibliographic Details
Main Authors: Tao Yuan-Xiang, Raja Srinivasa N, Yaster Myron, Guan Yun
Format: Article
Language:English
Published: SAGE Publishing 2007-10-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/3/1/29