Effective Synergy of Sorafenib and Nutrient Shortage in Inducing Melanoma Cell Death through Energy Stress

Effective Synergy of Sorafenib and Nutrient Shortage in Inducing Melanoma Cell Death through Energy Stress

Skin melanoma is one of the most aggressive and difficult-to-treat human malignancies, characterized by poor survival rates, thus requiring urgent novel therapeutic approaches. Although metabolic reprogramming has represented so far, a cancer hallmark, accumulating data indicate a high plasticity of...

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Bibliographic Details
Main Authors: Fernanda Antunes, Gustavo J. S. Pereira, Renata F. Saito, Marcus V. Buri, Mara Gagliardi, Claudia Bincoletto, Roger Chammas, Gian Maria Fimia, Mauro Piacentini, Marco Corazzari, Soraya Soubhi Smaili
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
apoptosis
energy stress
melanoma
autophagy
sorafenib
Online Access:https://www.mdpi.com/2073-4409/9/3/640

Internet

https://www.mdpi.com/2073-4409/9/3/640

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