Macrophage-derived myeloid differentiation protein 2 plays an essential role in ox-LDL-induced inflammation and atherosclerosis

Background: Atherosclerosis is a chronic inflammatory disease. Although Toll-like receptor 4 (TLR4) has been involved in inflammatory atherosclerosis, the exact mechanisms by which oxidized-low-density lipoproteins (ox-LDL) activates TLR4 and elicits inflammatory genesis are not fully known. Myeloid...

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Bibliographic Details
Main Authors: Taiwei Chen, Weijian Huang, Jinfu Qian, Wu Luo, Peiren Shan, Yan Cai, Ke Lin, Gaojun Wu, Guang Liang
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300815