An expedient, chemoselective N-chloroacetylation of aminoalcohols under metal-free bio-compatible conditions
We are reporting for the first time, efficient, highly chemoselective N-chloroacetylation of amino compounds (amino alcohols, amino acids) by chloroacetyl chloride, without compromising its high reactivity, to give chloroacetamides in phosphate buffer within 20 min. We have systematically studied th...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2018-10-01
|
Series: | Green Chemistry Letters and Reviews |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/17518253.2018.1544286 |