An expedient, chemoselective N-chloroacetylation of aminoalcohols under metal-free bio-compatible conditions

We are reporting for the first time, efficient, highly chemoselective N-chloroacetylation of amino compounds (amino alcohols, amino acids) by chloroacetyl chloride, without compromising its high reactivity, to give chloroacetamides in phosphate buffer within 20 min. We have systematically studied th...

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Bibliographic Details
Main Authors: B. S. Balaji, Neha Dalal
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Green Chemistry Letters and Reviews
Subjects:
Online Access:http://dx.doi.org/10.1080/17518253.2018.1544286