Chronic dosing with mirtazapine does not produce sedation in rats

Objective: Sedation/somnolence are major side effects of pharmacotherapies for depression, and negatively affect long-term treatment compliance in depressed patients. Use of mirtazapine (MIR), an atypical antidepressant approved for the treatment of moderate to severe depression with comorbid anxiet...

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Bibliographic Details
Main Authors: Alberto Salazar-Juárez, Susana Barbosa-Méndez, Paola Merino-Reyes, Maura Matus-Ortega, Jorge A. Hernández-Calderón, Benito Antón
Format: Article
Language:English
Published: Associação Brasileira de Psiquiatria (ABP) 2017-03-01
Series:Brazilian Journal of Psychiatry
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462017000300007&lng=en&tlng=en