A machine learning approach for identifying amino acid signatures in the HIV env gene predictive of dementia.

The identification of nucleotide sequence variations in viral pathogens linked to disease and clinical outcomes is important for developing vaccines and therapies. However, identifying these genetic variations in rapidly evolving pathogens adapting to selection pressures unique to each host presents...

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Bibliographic Details
Main Authors: Alexander G Holman, Dana Gabuzda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3498126?pdf=render