A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations

<p>Abstract</p> <p>Background</p> <p>The role of mutations in the serine protease inhibitor Kazal type 1 (<it>SPINK1</it>) gene in chronic pancreatitis is still a matter of debate. Active SPINK1 is thought to antagonize activated trypsin. Cases of <it>...

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Bibliographic Details
Main Authors: Schmitz Frank, Ansorge Nikolaus, Bulut Kerem, Einwächter Henrik, Hoffmann Peter, Felderbauer Peter, Schmidt Wolfgang E
Format: Article
Language:English
Published: BMC 2003-11-01
Series:BMC Gastroenterology
Subjects:
Online Access:http://www.biomedcentral.com/1471-230X/3/34