Cross talk of c-Jun N-terminal kinase and p38 map kinase modulate insulin and TNFα-stimulated VCAM-1 expression in rat aorta endothelial cells

VCAM-1 cell surface expression was determined by flow cytometry in rat aorta endothelial cells stimulated with insulin and/or Tumor Necrosis Factor-a in the absence or presence of short-hairpin RNA inhibitors of c-Jun N-terminal Kinase (JNK) and p38 MAP Kinase. Cells transfected with insulin alone e...

Full description

Bibliographic Details
Main Authors: Gregory B. Pott, Mark Tsurudome, Jamie Bui, Chelsea Gardner, Marc Lee Goalstone
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2016-10-01
Series:ADMET and DMPK
Subjects:
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/314