U2AF1 mutations in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome.

Somatic mutations of U2AF1 gene have recently been identified in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). In this study, we analyzed the frequency and clinical impact of U2AF1 mutations in a cohort of 452 Chinese patients with myeloid neoplasms. Mutations in U2AF1 were found...

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Bibliographic Details
Main Authors: Jun Qian, Dong-ming Yao, Jiang Lin, Wei Qian, Cui-zhu Wang, Hai-yan Chai, Jing Yang, Yun Li, Zhao-qun Deng, Ji-chun Ma, Xing-xing Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3446943?pdf=render